Background: Epidemiological studies treat testicular germ cancer as a single disease, the behavior of the two histological types of cancer; seminoma and nonseminoma have differences in reproductive hormone secretion and impair fertility differently. Objective: To demonstrate that the serum concentration of pituitary hormones involved in fertility and spermatogenesis in the affected male is different in the two histological types. Methods: Were determined by radioimmunoassay or inmunoradiometric assay, luteinizing hormone, follicle stimulating hormone, total testosterone, prolactin, estradiol, human chorionic gonadotropin and alpha fetoprotein in 37 patients with germ cell cancer 15 seminoma and 22 nonseminoma and 35 controls. We analyzed the semen of patients, and were questioned about paternity before the cancer diagnosis. Results: Age was higher in patients with seminoma cancer, showed decreased luteinizing hormone, follicle stimulating hormone, and testosterone and increased estradiol and prolactin in nonseminoma compared with seminoma. In patients with nonseminoma they had 9 children, 5 were oligozoospermic, 3 azoospermic and 6 normal concentration, 8 did not provide sample, seminoma group they had eight children, only one azoospermic, nine normal concentration, and 5 did not provide sample.
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Neus Potau Vilalta , A. Skip to search form Skip to main content You are currently offline. Some features of the site may not work correctly. DOI: Las gonadotropinas regulan la funcion gonadal masculina y femenina, asi como la sintesis de las hormonas sexuales. Su cuantificacion se realiza por inmunoanalisis tanto basal como en respuesta a estimulos de analogos de la Gn-RH. View via Publisher.
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Hernando Rafael Medicine American journal of neurodegenerative disease Galicia-Castillo Medicine References Publications referenced by this paper. LH levels in women with polycystic ovarian syndrome: have modern assays made them irrelevant?
Stella Ruth Milsom , Martin C. Sowter , Marion Carter , B. Michael Besser Medicine John Newell-Price , Damian G. Grossman Medicine The Journal of clinical endocrinology and metabolism Ten , Maria I. New , Noel Keith Maclaren Medicine Diagnosis and differential diagnosis of Cushing's syndrome. James W. Relative contributions of inferior petrosal sinus sampling and pituitary imaging in the investigation of children and adolescents with ACTH-dependent Cushing's syndrome.
Anne Lienhardt , Ashley B. Savage Medicine The Journal of clinical endocrinology and metabolism Definition and measurement of follicle stimulating hormone. Balen Biology, Medicine Endocrine reviews Serum inhibin A and inhibin B in healthy prepubertal, pubertal, and adolescent girls and adult women: relation to age, stage of puberty, menstrual cycle, follicle-stimulating hormone, luteinizing hormone, and estradiol levels.
Gonadotropinas (LH y FSH) y corticotropina (ACTH)
Gonadotropins are the main regulators of male and female gonadal functions and sexual hormone synthesis. In precocious puberty, hypogonadism or other pathological conditions affecting hypothalamic-pituitary-gonadal axis, LH and FSH measurement are useful and sensitive alone or together with sexual hormones testosterone and estradiol in order to establish the diagnosis.. Corticotropin ACTH is another pituitary hormone which regulates adrenal steroid synthesis. Hormone release is pulsatil throughout the day, but exhibits a diurnal pattern with levels being the highest in the early morning.
Hormona liberadora da gonadotropina
Mutation in the follicle-stimulating hormone receptor gene causes hereditary hypergonadotropic ovarian failure. Cell ; Identification of allelic variants in the follicle stimulating hormone receptor gene of females with and without hypergonadotropic amenorrhea. Fertil Steril ; A new syndrome of amenorrhea in association with hypergonadotropins and apparently normal ovarian follicular apparatus. Am J Obstet Gynecol ;
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