Background: Epidemiological studies treat testicular germ cancer as a single disease, the behavior of the two histological types of cancer; seminoma and nonseminoma have differences in reproductive hormone secretion and impair fertility differently. Objective: To demonstrate that the serum concentration of pituitary hormones involved in fertility and spermatogenesis in the affected male is different in the two histological types. Methods: Were determined by radioimmunoassay or inmunoradiometric assay, luteinizing hormone, follicle stimulating hormone, total testosterone, prolactin, estradiol, human chorionic gonadotropin and alpha fetoprotein in 37 patients with germ cell cancer 15 seminoma and 22 nonseminoma and 35 controls. We analyzed the semen of patients, and were questioned about paternity before the cancer diagnosis. Results: Age was higher in patients with seminoma cancer, showed decreased luteinizing hormone, follicle stimulating hormone, and testosterone and increased estradiol and prolactin in nonseminoma compared with seminoma. In patients with nonseminoma they had 9 children, 5 were oligozoospermic, 3 azoospermic and 6 normal concentration, 8 did not provide sample, seminoma group they had eight children, only one azoospermic, nine normal concentration, and 5 did not provide sample.

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Neus Potau Vilalta , A. Skip to search form Skip to main content You are currently offline. Some features of the site may not work correctly. DOI: Las gonadotropinas regulan la funcion gonadal masculina y femenina, asi como la sintesis de las hormonas sexuales. Su cuantificacion se realiza por inmunoanalisis tanto basal como en respuesta a estimulos de analogos de la Gn-RH. View via Publisher.

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Hernando Rafael Medicine American journal of neurodegenerative disease Galicia-Castillo Medicine References Publications referenced by this paper. LH levels in women with polycystic ovarian syndrome: have modern assays made them irrelevant?

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Gonadotropinas (LH y FSH) y corticotropina (ACTH)

Gonadotropins are the main regulators of male and female gonadal functions and sexual hormone synthesis. In precocious puberty, hypogonadism or other pathological conditions affecting hypothalamic-pituitary-gonadal axis, LH and FSH measurement are useful and sensitive alone or together with sexual hormones testosterone and estradiol in order to establish the diagnosis.. Corticotropin ACTH is another pituitary hormone which regulates adrenal steroid synthesis. Hormone release is pulsatil throughout the day, but exhibits a diurnal pattern with levels being the highest in the early morning.


Hormona liberadora da gonadotropina

Mutation in the follicle-stimulating hormone receptor gene causes hereditary hypergonadotropic ovarian failure. Cell ; Identification of allelic variants in the follicle stimulating hormone receptor gene of females with and without hypergonadotropic amenorrhea. Fertil Steril ; A new syndrome of amenorrhea in association with hypergonadotropins and apparently normal ovarian follicular apparatus. Am J Obstet Gynecol ;


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