International Myeloma Working Group. Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group. Br J Haematol ; International staging system for multiple myeloma. Journal Clinical Oncolology ;
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Solitary plasmacytoma of bone is defined by the presence of a single plasmacytoma in the absence of multiple osteolytic lesions or other findings compatible with multiple myeloma.
We report an older patient with solitary plasmacytoma of the sternum associated with atypical clinical findings which complicated diagnosis and possible progression to multiple myeloma. During admission, the patient developed refractory hyponatremia, superficial thrombophlebitis in the left upper limb, periorbital cellulitis, endophthalmitis, and sternal osteomyelitis. Serum protein electrophoresis showed a polyclonal increase in gamma globulins.
Biopsy result was compatible with plasmacytoma. A computed tomography scan showed no additional lesions. Progression was poor, with chronic renal failure exacerbated by probable tumor lysis syndrome, resulting in death.
Keywords: plasmacytoma; multiple myeloma; thrombophlebitis; hyponatremia. Evoluiu com tromboflebite superficial em membro superior esquerdo. A cultura revelou Staphilococcus aureus. Comparison of extramedullary plasmacytomas with solitary and multiple plasma cell tumors of bone. J Clin Oncol. Dimopoulos MA, Hamilos G. Solitary bone plasmacytoma and extramedullary plasmacytoma. Curr Treat Options Oncol. Plasmacytoma of bone, extramedullary plasmacytoma, and multiple myeloma: incidence and survival in the United States, Br J Haematol.
International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma. Lancet Oncol. Guidelines on the diagnosis and management of solitary plasmacytoma of bone and solitary extramedullary plasmacytoma. Mediterr J Hematol Infect Dis. DOI: Solitary plasmacytoma of bone and asymptomatic multiple myeloma. Clinical outcome of extramedullary plasmacytoma. Clinical and prognostic features of plasmacytomas: a multicenter study of Turkish Oncology Group-Sarcoma Working Party.
Am J Hematol. Skeletal Plasmacytoma: progression of disease and impact of local treatment; an analysis of SEER database. J Hematol Oncol. Solitary plasmacytoma: population-based analysis of survival trends and effect of various treatment modalities in the USA. BMC Cancer. Belo Horizonte: Coopmed; Rev Bras Clin Med. Rev Bras Ter Intensiva. Rocha PN. J Bras Nefrol. Oliveira AL, Nucci M. Rev Bras Hematol Hemoter. Received in November 6 Accepted em February 1 Home Past Issues Summary Vol.
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2011, Número 2
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